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All rights reserved. Ginger February 16, Julie L. Ginger, the rhizome of Zingiber officinale Roscoe, is best known for its role as a flavoring agent for food in Asian and Indian recipes.

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Since the 16th century, ginger has been used to treat various medical ailments and conditions, including migraines, arthritis, gingivitis, stroke, ulcers, constipation, diabetes, and nausea. It is important to note that not all ginger is the same. Genus Zingiber includes 85 species of aromatic herbs from East Asia and tropical Australia. The most abundant pungent compounds, as well as the biologically active constituents of ginger root, include gingerols, shogaols, paradols, and zingerone.

Gingerols are the major active component in fresh ginger and shogaols are the more abundant active prostate cancer forums australia in dried ginger.

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Gingerol becomes shogaol upon dehydration of fresh ginger. To date, research studies have shown biological activities of ginger to include anti-inflammatory, antioxidant, antiemetic, antiapoptotic, antihyperglycemic, and anticancer properties.

Most recently, ginger was shown to improve wound healing in combination with curcumin, a member of the ginger family and another spice with powerful antioxidant and anti-inflammatory capabilities.

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Ginger is typically consumed in the form of fresh, dried powder; an encapsulated powder or liquid extract; slices preserved in syrup; dried and preserved with a sugar coating crystallized ginger ; or as a tea flavoring. In an early randomized trial in college students with self-reported high susceptibility to motion sickness, ginger was more effective than dimenhydrinate Dramamine and each was more effective than dried chickweed herb placebo in preventing gastrointestinal symptoms of vection-induced motion sickness.

The 40 cadets who ingested the ginger also reported fewer episodes of nausea, although the difference between the treatment and control groups was not statistically significant.

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Two studies comparing ginger at a 0. Because of the abundance, relative safety, and low cost of ginger, extensive scientific studies of the herb have been undertaken, to uncover possible additional therapeutic properties. Potential medical uses for ginger include reversing diabetic proteinuria,[1] lowering blood pressure and reducing blood levels of lipids and cholesterol,[1,12] reducing arthritis symptoms,[13] protecting normal tissue from radiation,[14,15] and inhibiting gastric ulcers.

Over the last decade, ginger has been found to be anticarcinogenic through many different pathways. It has been shown to prevent initiation, promotion, and progression of various types of cancer.

Additionally, ginger effectively suppresses ultraviolet B-induced skin carcinogenesis, as well as TPA O-tetradecanoylphorbolacetate -induced skin edema. Until recently, it was unclear whether ginger provided relief from chemotherapy-induced nausea.

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The majority of clinical trials investigating the efficacy of ginger for chemotherapy-induced nausea were plagued by design inadequacies, including small sample sizes and nonvalidated assessment methods. Jiang et al.

What's the Bottom-Line Message? Ginger has demonstrated effectiveness against nausea associated with motion sickness, cancer chemotherapy, pregnancy, and the postoperative period. Although ginger is generally regarded as safe and there is no evidence of danger with long-term use, a doctor should be consulted before starting supplementation. Therefore, products may vary in strength, purity, and effect.

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Always read product labels to verify thar the supplement contains Zingiber officinale Ginger Root. Common prostate cancer forums australia of ginger root include: fresh root, dried root, capsules, liquid extract, and tea. Use of supplements should always be discussed with a qualified healthcare provider. The most commonly reported side effects of ginger supplementation include bad taste in the mouth, heartburn, belching, bloating, and gas.

References: Financial Disclosure: The author has no signifi cant fi nancial interestor other relationship with the manufacturer of any products orproviders of any service mentioned in this article.

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References 1. Food Chem Toxicol 46 2 –, Food Chem Toxicol 45 5 –, Roseville, CA, Prima Publishing, Zick SM, Djuric Z, Ruffin MT, et al: Pharmacokinetics of 6-gingerol, 8-gingerol, gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects. Cancer Epidemiol Biomarkers Prev 17 8 –, Bhagavathula N, Warner RL, DaSilva M, et al: A combination prostate cancer forums australia curcumin and ginger extract improves abrasion wound healing in corticosteroid-impaired hairless rat skin.

Wound Repair Regen 17 3 –, Lancet 1 –, A controlled trial on the open sea. Acta Otolaryngol –49, J Altern Complement Med 15 3 –, The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery.

Anaesthesia 45 8 –, Anaesthesia 48 8 –, Eur J Pharmacol –65, J Altern Complement Med 11 1 –, Pharmacol Biochem Behav 84 2 –, Jagetia GC, Baliga MS, Venkatesh P, et al: Influence of ginger rhizome Zingiber officinale Rosc on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation.

Radiat Res 5 –, Anticancer Res 23 5A –, Forum Nutr –, Am J Chin Med 30 –, Manju V, Nalini N: Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer.

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Clin Chim Acta –67, Cancer Res 56 5 –, Park KK, Chun KS, Lee JM, et al: Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice.